In this zany road trip comedy, John (played by Ethan Suplee) and Sam (portrayed by Kevin Connolly) are two best friends yearning for a getaway. They decide to embark on a journey from Washington, D.C., to New Orleans to experience the excitement of Mardi Gras. During their travels, they accidentally hit a man with their car. The unfortunate victim, Tyrone (played by Coolio), turns out to be a fugitive who meets his end shortly after the incident.