In “The Gamers: Hands of Fate,” we follow Cass (played by Brian Lewis) on his quest to clinch the world championship in a collectible card game, while also hoping to win the heart of Natalie (Trin Miller), a leading player in the game. Simultaneously, in the distant realm of Countermay, Myriad (Samara Lerman) starts to feel that destiny is working against her as she strives to defend her kingdom from a relentless undead army. Set against the backdrop of Gen Con Indy, a major gaming convention in the Midwest, this fantasy comedy from the creators of “Dorkness Rising” and “JourneyQuest” continues the expansive, decade-long saga that began with “The Gamers.”