As the full moon ascends over Beacon Hills, a formidable menace is unleashed. The howls of wolves echo once more, summoning Banshees, Werecoyotes, Hellhounds, Kitsunes, and all manner of nocturnal shapeshifters. However, it is up to Scott McCall, a Werewolf who has outgrown his teenage years but remains an Alpha, to rally new comrades and bring together old allies to confront what might be their most formidable and lethal adversary yet.