At just sixteen, Misao Makimachi, who appears even younger, is already a proficient and capable member of the Oniwabanshu ninja clan. This is a stroke of luck for Misao, as her ninja skills might be the only thing keeping her alive when her quest to find the clan’s leader, Aoshi Shinomori, unexpectedly brings her face-to-face with a more perilous adversary and a conspiracy to topple the Meiji government. She soon becomes entangled in the affairs of the legendary assassin Hitokiri Battosai, now known as Kenshin Himura, who wields a reverse-blade sword. Misao is drawn into a dangerous plot against Makoto Shishio, who is masterminding a takeover of Japan, starting with Kyoto!